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Senior Scientist (DMPK) - Dundee

Scientific and Drug Discovery - Other
Ref: 980 Date Posted: Monday 11 Jun 2018
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Senior Scientist – DMPK

Entrust are currently supporting an impressive, growing science led business who are focused on delivering a comprehensive platform of services to clients requiring innovative science based solutions.

The role is offered on a full time permanent basis and is based on their site in Dundee.

The Senior Scientist position is a pivotal role within the Analytical Sciences Team and will be focussed on supporting DMPK activities (regulatory and non-regulatory) 

You will be responsible for driving all lab based activities relating to DMPK performed at the Dundee site and would work closely with the Team Leader of Analytical Sciences, Principal Scientists and Quality Assurance to ensure that work is resourced and executed to the highest scientific and regulatory standards. You will also work with operational management, business development and senior management on the strategic development of the business

General Responsibilities:

  • In conjunction with the Team Leader of Analytical Sciences and Principal Scientists, plan and execute all DMPK work within agreed timelines.
  • Act as Study Director, Principal Investigator or Analytical Phase Manager (where appropriate) for regulatory and non-regulatory studies (DMPK).
  • Develop chromatographic methods (LC-MS, LC-MS/MS, GC-MS, HPLC and GC) for bioanalytical support of DMPK studies to current regulatory (FDA/EMEA) standards
  • When required, assist in the Study analysis of all bioanalytical and DMPK studies (regulatory and non-regulatory) performed on-site.
  • Contribute and author scientific publications
  • Act as mentor to less experienced members of the organisation
  • Operate in line with the company protocols and business strategy
  • Author and assist in the review of SOPs and other business process documents
  • Act as an ambassador for the business and in doing so proactively promoting the company brand and values both internally and externally.
  • Pro-actively identify opportunities for continuous improvement, profitability, quality and efficient ways of working.
  • Comply with health and safety requirements of the site as stated within company policy, procedure and practice.
  • Communicating effectively with colleagues throughout the business to share resources, technical knowledge and generally support all forms of business activity.

Ideally you will have a strong background in the following:

  • An ideal candidate for the role of DMPK Scientist will be educated to PhD level in Chemistry, Biochemistry or Pharmacology
  • Extensive knowledge and experience of in vitro small molecule ADME/DMPK essential.
  • Experience of in vivo small molecule ADME/DMPK highly advantageous
  • Experience of acting as Study Director, Principal Investigator and/or Analytical Phase Manager highly advantageous.
  • Experience with modern LC-MS(/MS) equipment essential (Sciex equipment and Analyst software highly advantageous).
  • Experience of supporting bioanalytical studies/discovery PK highly advantageous.
  • Experience of supporting metabolite identification studies and associated techniques (NMR, Radio detection etc.)  highly advantageous
  • Knowledge of market conditions, opportunities and competition desirable.
  • Understanding of customer base and commercial awareness also desirable.

My client offers:

  • A great working environment
  • Great Career Progression
  • Market Leading Staff Salary
  • Outstanding Company Benefits  

If you are interested in discussing things further then please contact me on 01224 608988 or email suzi@entrustpeople.co.uk

Entrust People are a specialist European life sciences resourcing partner who is dedicated to finding the best talent in the niche disciplines which our business supports